PRODUCT SHIPPED FROM HOLLAND
Reductil / Sibutramine or Regenon appetite suppressant pills is a very popular diet that is used to help men and women with weight loss issues. The people who seem to benefit the most from Reductil are those who are severely obese. People who are under 16 years of age or pregnant and nursing women should not use Reductil.
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Sibutramine was withdrawn from the U.S. market in October 2010. Sibutramine affects chemicals in the brain that affect weight maintenance. Sibutramine is used together with diet and exercise to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.
Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours.
At 1 year, adults receiving sibutramine, 10 to 15 mg/d, lost an average of 4.5 kg (9.8 pounds) more than adults receiving placebo. Adults taking sibutramine for 1 year are 19% to 34% more likely to achieve 5% weight loss and 12% to 31% more likely to achieve 10% weight loss than those taking placebo.